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	<title>Comments on: Italian study: Thimerosal not linked to autism</title>
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	<link>http://www.joannejacobs.com/2009/01/italian-study-thimerosal-not-linked-to-autism/</link>
	<description>Thinking and Linking by Joanne Jacobs</description>
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		<title>By: Andy Freeman</title>
		<link>http://www.joannejacobs.com/2009/01/italian-study-thimerosal-not-linked-to-autism/#comment-43479</link>
		<dc:creator>Andy Freeman</dc:creator>
		<pubDate>Sun, 01 Feb 2009 18:31:37 +0000</pubDate>
		<guid isPermaLink="false">http://joannejacobs.com/?p=7376#comment-43479</guid>
		<description>&gt; I just included the link to point out that researchers are definitely looking at what is explaining the rise in autism diagnosis.

I&#039;ve no doubt that they&#039;re looking.  However, the question is whether they&#039;re looking in a way that would tell us anything useful.

Let&#039;s put it another way.  Is there any possible evidence that would convince the &quot;vaccines cause autism&quot; folks that vaccines don&#039;t cause autism.  If there isn&#039;t ....

I don&#039;t have a position wrt autism because all of the evidence (for any conclusion) that I&#039;ve seen is pretty bad.  However, it&#039;s pretty clear that it&#039;s a religious issue, where evidence doesn&#039;t matter, for the vast majority of the folks involved.</description>
		<content:encoded><![CDATA[<p>&gt; I just included the link to point out that researchers are definitely looking at what is explaining the rise in autism diagnosis.</p>
<p>I&#8217;ve no doubt that they&#8217;re looking.  However, the question is whether they&#8217;re looking in a way that would tell us anything useful.</p>
<p>Let&#8217;s put it another way.  Is there any possible evidence that would convince the &#8220;vaccines cause autism&#8221; folks that vaccines don&#8217;t cause autism.  If there isn&#8217;t &#8230;.</p>
<p>I don&#8217;t have a position wrt autism because all of the evidence (for any conclusion) that I&#8217;ve seen is pretty bad.  However, it&#8217;s pretty clear that it&#8217;s a religious issue, where evidence doesn&#8217;t matter, for the vast majority of the folks involved.</p>
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		<title>By: Cardinal Fang</title>
		<link>http://www.joannejacobs.com/2009/01/italian-study-thimerosal-not-linked-to-autism/#comment-43478</link>
		<dc:creator>Cardinal Fang</dc:creator>
		<pubDate>Fri, 30 Jan 2009 19:09:28 +0000</pubDate>
		<guid isPermaLink="false">http://joannejacobs.com/?p=7376#comment-43478</guid>
		<description>The account at the link is poorly written, oops, sorry. In particular, it confuses a 56% increase with a 56 percentage point increase, an atrocious error, and there are other problems. The full article is pay-to-read, but here&#039;s the &lt;a href=&quot;http://www.epidem.com/pt/re/epidemiology/abstract.00001648-200901000-00016.htm;jsessionid=JDTWbSQlKcrxyXbZzhL5hnnhctsSfbp2211XYML1vwLTvjCsfVLG!-348297060!181195629!8091!-1&quot; rel=&quot;nofollow&quot;&gt; abstract&lt;/a&gt;. I have not read the full article; I just included the link to point out that researchers are definitely looking at what is explaining the rise in autism diagnosis.</description>
		<content:encoded><![CDATA[<p>The account at the link is poorly written, oops, sorry. In particular, it confuses a 56% increase with a 56 percentage point increase, an atrocious error, and there are other problems. The full article is pay-to-read, but here&#8217;s the <a href="http://www.epidem.com/pt/re/epidemiology/abstract.00001648-200901000-00016.htm;jsessionid=JDTWbSQlKcrxyXbZzhL5hnnhctsSfbp2211XYML1vwLTvjCsfVLG!-348297060!181195629!8091!-1" rel="nofollow"> abstract</a>. I have not read the full article; I just included the link to point out that researchers are definitely looking at what is explaining the rise in autism diagnosis.</p>
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		<title>By: Andy Freeman</title>
		<link>http://www.joannejacobs.com/2009/01/italian-study-thimerosal-not-linked-to-autism/#comment-43477</link>
		<dc:creator>Andy Freeman</dc:creator>
		<pubDate>Fri, 30 Jan 2009 17:19:10 +0000</pubDate>
		<guid isPermaLink="false">http://joannejacobs.com/?p=7376#comment-43477</guid>
		<description>&gt; “A study by researchers at the UC Davis M.I.N.D. Institute has found that the seven- to eight-fold increase in the number children born in California with autism since 1990 cannot be explained by either changes in how the condition is diagnosed or counted — and the trend shows no sign of abating.”

The account at the link doesn&#039;t support the conclusion.

From the article: &quot;Hertz-Picciotto and Delwiche correlated the number of cases of autism reported between 1990 and 2006 with birth records and excluded children not born in California. They used Census Bureau data to calculate the rate of incidence in the population over time and examined the age at diagnosis of all children ages two to 10 years old.&quot;

Whilel that methodology does eliminate migration, it tells us nothing about how diagnosis may have changed.  At best, it tells us how relative-to-age diagnosis changed over time but doesn&#039;t tell us anything more about different times.

For example, suppose that we ignored 75% 5 year olds in 1990.  If we then started looking at half of the 5, that methodology would tell us that the rate of diagnosis in 5 went up by 50%.  Yet, that methodology can&#039;t tell us what fraction of any of those populations was tested or whether the testing criteria changed.</description>
		<content:encoded><![CDATA[<p>&gt; “A study by researchers at the UC Davis M.I.N.D. Institute has found that the seven- to eight-fold increase in the number children born in California with autism since 1990 cannot be explained by either changes in how the condition is diagnosed or counted — and the trend shows no sign of abating.”</p>
<p>The account at the link doesn&#8217;t support the conclusion.</p>
<p>From the article: &#8220;Hertz-Picciotto and Delwiche correlated the number of cases of autism reported between 1990 and 2006 with birth records and excluded children not born in California. They used Census Bureau data to calculate the rate of incidence in the population over time and examined the age at diagnosis of all children ages two to 10 years old.&#8221;</p>
<p>Whilel that methodology does eliminate migration, it tells us nothing about how diagnosis may have changed.  At best, it tells us how relative-to-age diagnosis changed over time but doesn&#8217;t tell us anything more about different times.</p>
<p>For example, suppose that we ignored 75% 5 year olds in 1990.  If we then started looking at half of the 5, that methodology would tell us that the rate of diagnosis in 5 went up by 50%.  Yet, that methodology can&#8217;t tell us what fraction of any of those populations was tested or whether the testing criteria changed.</p>
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		<title>By: Lightly Seasoned</title>
		<link>http://www.joannejacobs.com/2009/01/italian-study-thimerosal-not-linked-to-autism/#comment-43476</link>
		<dc:creator>Lightly Seasoned</dc:creator>
		<pubDate>Fri, 30 Jan 2009 14:22:33 +0000</pubDate>
		<guid isPermaLink="false">http://joannejacobs.com/?p=7376#comment-43476</guid>
		<description>Mental Retardation (MR) is still an official designation.</description>
		<content:encoded><![CDATA[<p>Mental Retardation (MR) is still an official designation.</p>
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		<title>By: Cardinal Fang</title>
		<link>http://www.joannejacobs.com/2009/01/italian-study-thimerosal-not-linked-to-autism/#comment-43475</link>
		<dc:creator>Cardinal Fang</dc:creator>
		<pubDate>Fri, 30 Jan 2009 05:24:31 +0000</pubDate>
		<guid isPermaLink="false">http://joannejacobs.com/?p=7376#comment-43475</guid>
		<description>&quot;A study by researchers at the UC Davis M.I.N.D. Institute has found that the seven- to eight-fold increase in the number children born in California with autism since 1990 cannot be explained by either changes in how the condition is diagnosed or counted — and the trend shows no sign of abating.&quot; -- &lt;a href=&quot;http://www.sciencedaily.com/releases/2009/01/090108095429.htm&quot; rel=&quot;nofollow&quot;&gt;Science Daily&lt;/a&gt; reporting on a study published this month in the journal Epidemiology.</description>
		<content:encoded><![CDATA[<p>&#8220;A study by researchers at the UC Davis M.I.N.D. Institute has found that the seven- to eight-fold increase in the number children born in California with autism since 1990 cannot be explained by either changes in how the condition is diagnosed or counted — and the trend shows no sign of abating.&#8221; &#8212; <a href="http://www.sciencedaily.com/releases/2009/01/090108095429.htm" rel="nofollow">Science Daily</a> reporting on a study published this month in the journal Epidemiology.</p>
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		<title>By: momof4</title>
		<link>http://www.joannejacobs.com/2009/01/italian-study-thimerosal-not-linked-to-autism/#comment-43474</link>
		<dc:creator>momof4</dc:creator>
		<pubDate>Fri, 30 Jan 2009 00:19:50 +0000</pubDate>
		<guid isPermaLink="false">http://joannejacobs.com/?p=7376#comment-43474</guid>
		<description>Many years ago, many kids were simply labelled &quot;retarded&quot;; a label I have not heard in decades and which is now unacceptable. I think that a very significant part of the large increase in autism (which now includes various points on the autism spectrum disorder diagnosis) is a change in the parameters for diagnosis. The assortive mating hypothesis also makes sense.</description>
		<content:encoded><![CDATA[<p>Many years ago, many kids were simply labelled &#8220;retarded&#8221;; a label I have not heard in decades and which is now unacceptable. I think that a very significant part of the large increase in autism (which now includes various points on the autism spectrum disorder diagnosis) is a change in the parameters for diagnosis. The assortive mating hypothesis also makes sense.</p>
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		<title>By: Cardinal Fang</title>
		<link>http://www.joannejacobs.com/2009/01/italian-study-thimerosal-not-linked-to-autism/#comment-43473</link>
		<dc:creator>Cardinal Fang</dc:creator>
		<pubDate>Thu, 29 Jan 2009 23:40:03 +0000</pubDate>
		<guid isPermaLink="false">http://joannejacobs.com/?p=7376#comment-43473</guid>
		<description>Kate, 

I know of two kids at CalTech. Both are on the autism spectrum. I&#039;m sure there are plenty of non-autistics there, but autistic people are well represented at CalTech.

The assortative mating theory is not that there&#039;s some recessive autism gene, but rather that autism is a kind of super-nerdiness. That is, nerds are interested in systems rather than people, but an ordinary nerd has some ability to read and understand people. According to the theory, autistic people are nerds, but more so-- they&#039;re interested in systems to the exclusion of people, lacking the ability to understand what other people are thinking and feeling.</description>
		<content:encoded><![CDATA[<p>Kate, </p>
<p>I know of two kids at CalTech. Both are on the autism spectrum. I&#8217;m sure there are plenty of non-autistics there, but autistic people are well represented at CalTech.</p>
<p>The assortative mating theory is not that there&#8217;s some recessive autism gene, but rather that autism is a kind of super-nerdiness. That is, nerds are interested in systems rather than people, but an ordinary nerd has some ability to read and understand people. According to the theory, autistic people are nerds, but more so&#8211; they&#8217;re interested in systems to the exclusion of people, lacking the ability to understand what other people are thinking and feeling.</p>
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		<title>By: Lightly Seasoned</title>
		<link>http://www.joannejacobs.com/2009/01/italian-study-thimerosal-not-linked-to-autism/#comment-43472</link>
		<dc:creator>Lightly Seasoned</dc:creator>
		<pubDate>Thu, 29 Jan 2009 23:34:23 +0000</pubDate>
		<guid isPermaLink="false">http://joannejacobs.com/?p=7376#comment-43472</guid>
		<description>And Bill Gates is a classic example of an undiagnosed autistic kid.  Yes, I think there is some over-diagnosis going on (especially attributing other problems to autism), but I think it is the catching of these &quot;quirky kids&quot; that is causing some of the bump in numbers.</description>
		<content:encoded><![CDATA[<p>And Bill Gates is a classic example of an undiagnosed autistic kid.  Yes, I think there is some over-diagnosis going on (especially attributing other problems to autism), but I think it is the catching of these &#8220;quirky kids&#8221; that is causing some of the bump in numbers.</p>
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		<title>By: Kate</title>
		<link>http://www.joannejacobs.com/2009/01/italian-study-thimerosal-not-linked-to-autism/#comment-43471</link>
		<dc:creator>Kate</dc:creator>
		<pubDate>Thu, 29 Jan 2009 23:02:47 +0000</pubDate>
		<guid isPermaLink="false">http://joannejacobs.com/?p=7376#comment-43471</guid>
		<description>Cardinal Fang--I vote for the mating theory. You should see CalTech and JPL--so many parents of autistic kids, and then you meet dad, who&#039;s like Bill Gates. 

Back in the day, lots of those guys didn&#039;t marry and if they did, they found some woman not like themselves, thus sidestepping the changes of two recessive genes. But today--nerds galore.</description>
		<content:encoded><![CDATA[<p>Cardinal Fang&#8211;I vote for the mating theory. You should see CalTech and JPL&#8211;so many parents of autistic kids, and then you meet dad, who&#8217;s like Bill Gates. </p>
<p>Back in the day, lots of those guys didn&#8217;t marry and if they did, they found some woman not like themselves, thus sidestepping the changes of two recessive genes. But today&#8211;nerds galore.</p>
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		<title>By: Andy Freeman</title>
		<link>http://www.joannejacobs.com/2009/01/italian-study-thimerosal-not-linked-to-autism/#comment-43470</link>
		<dc:creator>Andy Freeman</dc:creator>
		<pubDate>Thu, 29 Jan 2009 15:59:58 +0000</pubDate>
		<guid isPermaLink="false">http://joannejacobs.com/?p=7376#comment-43470</guid>
		<description>&gt; But that doesn’t explain the explosive growth in autism in the couple of decades.

Different diagnosis capabilities does, as does a change in incentives.

I&#039;ve no doubt that autism researchers are correct when they claim that many autistics weren&#039;t diagnosed in the past.  Is it really likely that we&#039;re currently diagnosing perfectly now?  Is it impossible that we&#039;re overdiagnosing?</description>
		<content:encoded><![CDATA[<p>&gt; But that doesn’t explain the explosive growth in autism in the couple of decades.</p>
<p>Different diagnosis capabilities does, as does a change in incentives.</p>
<p>I&#8217;ve no doubt that autism researchers are correct when they claim that many autistics weren&#8217;t diagnosed in the past.  Is it really likely that we&#8217;re currently diagnosing perfectly now?  Is it impossible that we&#8217;re overdiagnosing?</p>
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